发布时间:2023-11-26
赵祯,博士,讲师。
2013.09-2017.07,江南大学,生物技术专业,学士。
2017.09-2023.06,中国科公司大学,生物化学与分子生物学,博士。
二、主要研究方向
1.菌株发酵性状调控机理解析与优化;
2.大宗化学品发酵菌株构建。
三、科研项目
(1) 国家自然科学基金委员会面上项目, 32071424, 嗜热毁丝霉苹果酸发酵菌种杂酸降低代谢工程改造研究,参与;
(2) 国家自然科学基金委员会面上项目, 31972879, 工业丝状真菌嗜热毁丝霉内质网发育规律及人工重编程改造研究, 参与。
四、学术论文
(1) Zhen Zhao; Shuying Gu; Defei Liu; Dandan Liu; Bingchen Chen; Jingen Li; Chaoguang Tian; The putative methyltransferase LaeA regulates mycelium growth and cellulase production in Myceliophthora thermophila, Biotechnol Biofuels Bioprod, 2023, 16(1): 58.
(2) Shuying Gu#; Zhen Zhao#; Fanglei Xue; Defei Liu; Qian Liu; Jingen Li; Chaoguang Tian; The arabinose transporter MtLat-1 is involved in hemicellulase repression as a pentose transceptor in Myceliophthora thermophila, Biotechnol Biofuels Bioprod, 2023, 16(1): 51.
(3) Fanglei Xue#; Zhen Zhao#; Shuying Gu; Meixin Chen; Jing Xu; Xuegang Luo; Jingen Li; Chaoguang Tian; The transcriptional factor Clr-5 is involved in cellulose degradation through regulation of amino acid metabolism in Neurospora crassa, BMC Biotechnol, 2023, 23(1): 50.
(4) Jingen Li#, Bingchen Chen#, Shuying Gu#, Zhen Zhao, Qian Liu, Tao Sun, Yongli Zhang, Taju Wu, Defei Liu, Wenliang Sun, Chaoguang Tian; Coordination of consolidated bioprocessing technology and carbon dioxide fixation to produce malic acid directly from plant biomass in Myceliophthora thermophila, Biotechnol Biofuels, 2021, 14: 186.
(5) Hanyu Wang#, Tao Sun#, Zhen Zhao, Shuying Gu, Qian Liu, Taju Wu, Depei Wang, Chaoguang Tian, Jingen Li, Transcriptional Profiling of Myceliophthora thermophila on Galactose and Metabolic Engineering for Improved Galactose Utilization, Front Microbiol, 2021, 12: 664011.
五、专利
1.一种促进宿主细胞生长速率及其底物利用的方法及应用:中国,ZL202010892096.2
2.一种调控sgRNA 转录的启动子、表达载体,及其基因组编辑系统和应用:中国,ZL201910834799.7
3.一种合成丙二酸的方法及应用:中国,202111372515.0
4.一种提高丝状真菌有机酸合成能力的方法:中国,2020109734010
5.一种提高丝状真菌有机酸合成的方法及应用:中国,202310536840.9