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王卿卿

发布时间:2023-11-26

一、个人简介

王卿卿,博士,硕士研究生导师,校聘教授。河北微生物学会会员、河北生化学会会员。

2001.09-2005.06,伟德国际victor官网,制药工程专业,学士。

2005.09-2008.06,伟德国际victor官网,生物化工专业,硕士。

2009.09-2014.06,中国科公司大学,生物化工专业,博士。

二、主要研究方向

1. 液体活检领域中循环肿瘤细胞的检测,主要包括循环肿瘤细胞的捕获及分子检测;

2. 蛋白质纯化及修饰;

3. 药物制剂方面的研究;

三、科研项目

1.河北省教育厅项目,基于循环多组学的胰腺癌早期检测方法开发,主持

2.横向课题,用于细胞染色的PD-L1抗体的开发及性能验证,主持

3.横向课题,用于富集宫颈癌细胞的免疫磁珠开发及性能验证, 主持

四、学术论文

(1) Qingqing Wang; Lijing Sun; Shaoyang Ji; Dawei Zhao; Jiaxin Liu; Zhiguo Su; Tao Hu ; Reversible protection of Cys-93(β) by PEG alters the structural and functional properties of the PEGylated hemoglobin, Biochim Biophys Acta, 2014, 1844(7): 1201-1207.

(2) Qingqing Wang; Tao Hu; Lijing Sun; Shaoyang Ji; Dawei Zhao; Jiaxin Liu; Guanghui Ma; Zhiguo Su ; CO binding improves the structural, functional, physical and anti-oxidation properties of the PEGylated hemoglobin, Artif Cells Nanomed Biotechnol, 2015, 43(1): 18-25 .

(3) Dawei Zhao; Yongdong Liu; Yinjue Wang; Xiunan Lia; Qingqing Wang; Membrane Combined with Hydrophilic Macromolecules Enhances Protein Refolding at High Concentration. Process Biochemistry, Process Biochemistry, 2014, 49: 1129-1134.

(4) Fei Peng; Yongdong Liu; Xiunan Li; Lijing Sun; Dawei Zhao; Qingqing Wang; Guanghui Ma; Zhiguo Su ; PEGylation of G-CSF in organic solvent markedly increase the efficacy and reactivity through protein unfolding, hydrolysis inhibition and solvent effect, Journal of Biotechnology, 2014, 170: 42-49.

(5) Tao Hu; Dongxia Li; Jun Wang; Qingqing Wang; Yangui Liang; Yanlei Su; Guanghui Ma; ZhiguoSu; Shihua Wang ; Propylbenzmethylation at Val-1(α) markedly increases the tetramer stability of the PEGylated hemoglobin: A comparison with propylation at Val-1(α), Biochimica et Biophysica Acta-general subjects, 2012, 1820: 2044-2051.