一、个人简介

侯力睿，博士，讲师，邮箱：houlirui@hebust.edu.cn。

2015.09-2019.07，西北农林科技大学，食品质量与安全专业，学士。

2019.09-2025.07，中国农业大学，食品科学与工程专业，博士。

二、主要研究方向

1. 食源性功能因子的评价及机制研究

2. 食品中危害因子毒性效应评价和毒理学研究

3. 功能性食品开发与研究

三、科研项目

1. 十四五国家重点研发计划青年科学家项目：微藻源新型食品全链条风险因子高效识别与阻控关键技术研究（2022YFF1102800），参与。

2. 十三五国家重点研发计划子课题：畜禽中典型兽药混合污染安全性体外评价与应用（2018YFC1603005），参与。

四、学术论文

累计发表论文13篇，其中以第一作者身份发表7篇（SCI论文6篇，中文核心1篇）。

[1] Hou L, Fu Y, Zhao C, Fan L, Hu H, Yin S*. Short-term exposure to ciprofloxacin and microplastic leads to intrahepatic cholestasis, while long-term exposure decreases energy metabolism and increases the risk of obesity[J]. Environment International, 2025, 199: 109511.

[2] Hou L, Fu Y, Zhao Y, Dai C, Zhao C, Fan L, Hu H, Yin S*. Ciprofloxacin disrupts testosterone synthesis in mice by inhibiting NR4A1 expression, which downregulates StAR transcription[J]. Ecotoxicology and Environmental Safety, 2025, 302: 118511.

[3] Hou L, Fu Y, Zhao C, Fan L, Hu H, Yin S*. The research progress on the impact of antibiotics on the male reproductive system[J]. Environment International, 2024, 187: 108670.

[4] Hou L, Fu Y, Zhao C, Fan L, Hu H, Yin S*. Ciprofloxacin and enrofloxacin can cause reproductive toxicity via endocrine signaling pathways[J]. Ecotoxicology and Environmental Safety, 2022, 244: 114049.

[5] Hou L, Liu F, Zhao C, Fan L, Hu H, Yin S*. Combination of oxytetracycline and quinocetone synergistically induces hepatotoxicity via generation of reactive oxygen species and activation of mitochondrial pathway[J]. Toxicology Mechanisms and Methods, 2022, 32 (1): 49-57.

[6] Hou L, Liu S, Zhao C, Fan L, Hu H, Yin S*. The combination of T-2 toxin and acrylamide synergistically induces hepatotoxicity and nephrotoxicity via the activation of oxidative stress and the mitochondrial pathway[J]. Toxicon, 2021, 189: 65-72.

[7] 侯力睿,傅榆涵,赵冲,扈洪波,尹淑涛*. 兽药抗生素对生态环境的混合毒性研究进展[J]. 环境化学, 2021, 40 (1): 55-64.

[8] Fu C, Hou L, Chen D, Huang T, Yin S*, Ding P, Liao Q, Huang X, Xiong Y, Ge J, Li X*. Targeted Detoxification of Aflatoxin B1 in Edible Oil by an Enzyme-Metal Nanoreactor[J]. Journal of Agricultural and Food Chemistry, 2024, 72 (11): 5966–5974.

[9] Fu Y, Hou L, Zhao Y, Han K, Zhao C, Hu H*, Yin S*. The Physiological Role of Copper: Dietary Sources, Metabolic Regulation, and Safety Concerns[J]. Clinical Nutrition, 2025, 48: 161-179.

[10] Fu Y, Hou L, Zhao Y, Han K, Zhao C, Hu H, Yin S*. Epigallocatechin Gallate Promotes Cuproptosis via the MTF1/ATP7B Axis in Hepatocellular Carcinoma[J]. Cells, 2025, 14(6): 391.

[11] Liu G, Han S, Hou L, Zeng L, Jiang Y, Liu C, Che H*. Sialic Acid (Neu5Ac)-Driven Modulation of Intestinal Sialylation as a Novel Approach to Mitigating Allergic Reactions to Shrimp Tropomyosin[J]. Journal of Agricultural and Food Chemistry, 2025, 73(22): 13516–13530.

[12] 傅榆涵,侯力睿,赵冲,扈洪波,尹淑涛*. 恩诺沙星、喹烯酮、土霉素和硫酸多黏菌素B对细胞的联合毒性研究[J]. 中国畜牧兽医, 2022, 49 (2): 687-699.

[13] 胡瑶琪,侯力睿,傅榆涵,尹淑涛*. 环丙沙星和恩诺沙星联合肝毒性及其机制研究[J]. 中国兽医科学, 2021, 51 (4): 509-517.